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{ Category Archives } Research methods

Treatments to enhance recovery from the vegetative and minimally conscious states: ethical issues surrounding efficacy studies.

by John Whyte, MD, PhD.
Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network, Philadelphia, Pennsylvania, USA.
Randomized double-blind placebo-controlled trials have been argued to provide the strongest test of efficacy and, as such, are important tools for advancing the evidence base supporting rehabilitation treatment. However, such trials present difficult ethical issues, because one group, by definition, receives [...]

MossRehab Develops Gait Lab Protocol

Dr. Esquenazi is equally committed to streamlining gait analysis technology for aligning prosthetics and orthotics. “The current state of the art in smaller clinics is a prosthetist or clinician watching the patient walk,” explains Dr. Esquenazi. “Results are subjective and inconsistent – clinician experience and patient subjectivity are just two of many variables.”
In a multi-year [...]

Applying evidence standards to rehabilitation research.

by Mark V. Johnston, PhD, Mark Sherer, PhD, John Whyte, MD, PhD.Outcomes Research, Kessler Medical Rehabilitation Research and Education Corporation, West Orange, New Jersey, USA.OBJECTIVE: To describe evidence grading methods employed in the systematic reviews in this special series of articles. To provide an overview of results of these reviews to critique the quality of [...]

Using treatment theories to refine the designs of brain injury rehabilitation treatment effectiveness studies.

by John Whyte, MD, PhD.
Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network, Philadelphia, PA, USA.
Many rehabilitation treatments are difficult to define, resulting in a lack of clarity about their essential “active ingredients.” Treatment theories can narrow the scope of possible active ingredients, by clearly specifying how the treatment is believed to act. Efficacy studies [...]