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{ Category Archives } Brain injury

The effects of bromocriptine on attention deficits after traumatic brain injury: a placebo-controlled pilot study.

by John Whyte, MD, PhD, Monica Vaccaro, MA, Patricia Grieb-Neff, MS, Tessa Hart, PhD, Marcia Polansky, ScD, H. Branch Coslett, MD Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network, Philadelphia, Pennsylvania. OBJECTIVE: To evaluate the effects of bromocriptine on a variety of aspects of attention, ranging from laboratory-based impairment measures to caregiver ratings and work productivity, [...]

Influence of botulinum toxin type A treatment of elbow flexor spasticity on hemiparetic gait.

by Alberto Esquenazi, MD, Nathaniel Mayer, MD, Roser Garreta, MD Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network, Philadelphia, Pennsylvania, USA. OBJECTIVE: To assess whether walking velocity could be improved in patients with disorders related to upper-motor neuron syndrome (UMNS) by treating elbow flexor spasticity with botulinum toxin type A (BoNTA). DESIGN: This was a [...]

Comparative impact of 2 botulinum toxin injection techniques for elbow flexor hypertonia.

by Nathaniel H. Mayer, MD, John Whyte, MD, PhD, Gunilla Wannstedt, MS, PT, Colin A. Ellis, ScB Department of Physical Medicine and Rehabilitation, Temple University School of Medicine, Philadelphia, PA, USA OBJECTIVE: To compare 2 techniques of botulinum toxin injection for elbow flexor hypertonia. DESIGN: Parallel-group, randomized, controlled trial with blinded outcome assessment. SETTING: Laboratory, [...]

The Moss Attention Rating Scale for traumatic brain injury: further explorations of reliability and sensitivity to change.

by John Whyte, MD, PhD, Tessa Hart, PhD, Colin A. Ellis, ScB, Inna Chervoneva, PhD Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network, Philadelphia, PA OBJECTIVE: To examine the interrater agreement and responsiveness to change of the Moss Attention Rating Scale (MARS), 22-item version, during acute inpatient rehabilitation after traumatic brain injury (TBI). DESIGN: Observational [...]

Nationwide Zolpidem Study Now Underway at Moss Rehabilitation Research Institute

After completing a pioneering study on vegetative patients’ response to the drug zolpidem (known as Ambien, but now available generically) researchers at Moss Rehabilitation Research Institute (MRRI) are embarking on a three-year, nationwide examination of how and why the drug has such a dramatic effect on some patients but not others. Case reports of the [...]

Dr. John Whyte Receives Moody Prize

John Whyte, MD, PhD, director of MossRehab Research Institute, is the recipient of the 2008 Robert L. Moody Prize for Distiguished Initiatives in Brain Injury Research and Rehabilition. As the Moody Prize recipient, Dr. Whyte will receive a $10,000 cash award and the Tiffany Pyramid. Internationally renowned experts in brain trauma will convene May 14 [...]

MossRehab’s Lokomat® Robot Improves Walking Ability

MossRehab’s recent acquisition of the Lokomat — a robotic training assistant consisting of an exoskeleton mounted above a treadmill — will greatly enhance the process of helping patients relearn how to walk. The Lokomat’s exoskeleton, pictured at right, wraps around a patient’s hips, knees, and lower back. Via a computer, it can be programmed to [...]

MossRehab’s Patient Outcomes in 2007 Exceed National and Regional Averages

MossRehab is committed to optimizing our patients’ function and quality of life. As part of this commitment to quality, we grade ourselves each year by quantifying the functional gains our patients make. Using the Functional Independence Measure™ (FIM™), an instrument widely employed in the rehabilitation industry, we track our patient’s admission and discharge status in [...]

Traumatic Brain Injury Program at Moss: Research and Results

In a split second, a patient’s life can be altered by traumatic brain injury (TBI). According to the Brain Injury Association of America, a traumatic brain injury occurs every 23 seconds. Called a “silent epidemic,” TBI has resulted in disability for more than 5.3 million Americans. The estimated lifetime cost of brain injury — including [...]

Gender and traumatic brain injury: do the sexes fare differently?

by Jonathan J. Ratcliff, Arlene I. Greenspan, Felicia C. Goldstein, Anthony Y. Stringer, Tamara Bushnik, Flora M. Hammond, MD, Thomas A. Novack, PhD, John Whyte, MD, PhD, David W. Wright. Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA. OBJECTIVE: To examine the relationship between gender and cognitive recovery 1 year following [...]

The effects of methylphenidate on command following and yes/no communication in persons with severe disorders of consciousness: a meta-analysis of n-of-1 studies.

by Robert T. Martin, MA, John Whyte, MD, PhD. Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network, Philadelphia, Pennsylvania, USA. OBJECTIVE: To determine the effects of methylphenidate (MPH) on command following and yes/no communication in brain injured patients with severe disorders of consciousness (DOC). DESIGN: A meta-analysis of a series of single-subject repeated crossover trials, [...]

Measuring recovery in new learning and memory following traumatic brain injury: a mixed-effects modeling approach.

by Bong-Chul Chu, Scott Millis, Juan Carlos Arango-Lasprilla, Robin Hanks, Thomas Novack, Tessa Hart. The Medstat Group, Santa Barbara, CA, USA. Patterns of recovery from traumatic brain injury (TBI) vary greatly across individuals. Using archival data from the Traumatic Brain Injury Model Systems, recovery of memory following TBI as measured by scores on the Rey [...]