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{ Monthly Archives } October 2008

Hand path priming in manual obstacle avoidance: Rapid decay of dorsal stream information.

by Steven A. Jax, PhD, David A. Rosebaum

Moss Rehabilitation Research Institute, Philadelphia, PA 19141, United States.

The dorsal, action-related, visual stream has been thought to have little or no memory. This hypothesis has seemed credible because functions related to the dorsal stream have been generally unsusceptible to priming from previous experience. Tests of this claim have [...]

Assessment of spatial attention and neglect with a virtual wheelchair navigation task.

by Laurel J. Buxbaum, PsyD, Mary Ann Palermo,  Dina Mastrogiovanni,  Mary Schmidt Read,  Ellen Rosenberg-Pitonyak,  Albert A. Rizzo, H. Branch Coslett
Moss Rehabilitation Research Institute, Philadelphia, PA, USA
A total of 9 participants with right-hemisphere stroke performed a new virtual reality (VR) wheelchair navigation test of lateralized spatial attention and neglect. The test consists of a [...]

Successful reduction of neuropathic pain associated with spinal cord injury via of a combination of intrathecal hydromorphone and ziconotide: a case report.

by Michael Saulino, MD
Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network, Philadelphia, PA.
STUDY DESIGN: Case report.
OBJECTIVES: To report a novel management strategy for neuropathic pain management after spinal cord injury.
SETTING: Outpatient spinal cord injury (SCI) clinic.
METHODS: The patient demonstrated two neuropathic pain syndromes, namely at- and below-level pain. These syndromes were recalcitrant to conservative measures [...]

Comparison of speeds used for the 15.2-meter and 6-minute walks over the year after an incomplete spinal cord injury: the SCILT Trial.

by H. Barbeau, PhD, R. Elashoff, PhD, D. Deforge, MD, J. Ditunno, MD, M. Saulino, MD, B.H. Dobkin, MD
McGill University/Institut de Readaptation de Montreal, Montreal, Quebec, Canada.
BACKGROUND: Timed walking speed for 6 to 15 m and the distance walked in 2 to 12 minutes are frequently used outcome measures in rehabilitation trials, presumably reflecting [...]

A practical overview of tizanidine use for spasticity secondary to multiple sclerosis, stroke, and spinal cord injury.

by Leonard Kamen, DO, Herbert R. Henney, Jacob D. Runyan
Albert Einstein Medical Center, Moss Rehabilitation Outpatient Center, Philadelphia, PA, USA. 
OBJECTIVE: Tizanidine is an imidazoline central alpha(2)-adrenoceptor agonist widely used to manage spasticity secondary to conditions such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI). While there is widespread use of tizanidine in clinical [...]

Structural consequences of diffuse traumatic brain injury: a large deformation tensor-based morphometry study.

by Junghoon Kim, Brian Avants, Sunil Patel, John Whyte, MD, PhD, Branch H. Coslett, MD, John Pluta, John A. Detre, James C. Gee

Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network, Philadelphia, PA

Traumatic brain injury (TBI) is one of the most common causes of long-term disability. Despite the importance of identifying neuropathology in individuals with chronic [...]

The dilemma of the control condition in experience-based cognitive and behavioural treatment research.

by Tessa Hart, PhD, Jesse R. Fan, Thomas A. Novak
Department of Rehabilitation Medicine, Jefferson Medical College, Philadelphia, PA, USA.
Rehabilitation using cognitive and behavioural treatment methods (i.e., experience-based interventions) faces particular challenges in improving its evidence base through rigorous studies such as randomised controlled trials (RCTs). Experience-based treatments are often complex, with multiple “active ingredients” that [...]

Impact of age on long-term recovery from traumatic brain injury.

by Carlos D. Marquez de la Plata, PhD, Tessa Hart, PhD, Flora M. Hammond, MD, Alan B. Frol, PhD, Anne Hudak, MD, Caryn R. Harper, MS, Therese M. O’Neil-Pirozzi, ScD, John Whyte, MD, PhD, Mary Carlile, MD, Ramon Diaz-Arrastia, MD, PhD

Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.
OBJECTIVE: To determine whether older persons are at increased risk for progressive functional decline [...]

The effects of bromocriptine on attention deficits after traumatic brain injury: a placebo-controlled pilot study.

by John Whyte, MD, PhD, Monica Vaccaro, MA, Patricia Grieb-Neff, MS, Tessa Hart, PhD, Marcia Polansky, ScD, H. Branch Coslett, MD

Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network, Philadelphia, Pennsylvania.

OBJECTIVE: To evaluate the effects of bromocriptine on a variety of aspects of attention, ranging from laboratory-based impairment measures to caregiver ratings and work productivity, in individuals [...]

Treatment of limb apraxia: moving forward to improved action.

by Laurel J. Buxbaum, PsyD, Kathleen Y. Haaland, Phd, Mark Hallett, MD, Lewis Wheaton, PhD, Kenneth M. Heilman, MD, Amy Rodriguez, MA, CCC-SLP, Leslie J. Gonzalez-Rothi, PhD
Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network, Philadelphia, PA.
Limb apraxia is a common disorder of skilled, purposive movement that is frequently associated with stroke and degenerative diseases such [...]

Influence of botulinum toxin type A treatment of elbow flexor spasticity on hemiparetic gait.

by Alberto Esquenazi, MD, Nathaniel Mayer, MD, Roser Garreta, MD
Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network, Philadelphia, Pennsylvania, USA.
OBJECTIVE: To assess whether walking velocity could be improved in patients with disorders related to upper-motor neuron syndrome (UMNS) by treating elbow flexor spasticity with botulinum toxin type A (BoNTA).
DESIGN: This was a prospective, open-label, multicenter, [...]

A Longitudinal Study of Actual and Perceived Activity Levels in Polio Survivors and Older Controls.

by Mary G. Klein, PhD, Leonard E. Braitman, PhD, Roberta Costello, MS, RN, Mary Ann Keenan, MD, Albert Esquenazi, MD

Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network, Philadelphia, PA; Thomas Jefferson University, Philadelphia PA.

OBJECTIVE: To examine factors associated with daily step activity, perceived activity, maximum walking speed, and walking speed reserve over time in polio [...]